2025 Golden Globes: Demi Moore Shares How She Overcame “Low Point” in Powerful Acceptance Speech

2025 Golden Globes: Demi Moore Details Pitfalls of Aging in Hollywood

Demi Moore is all substance at the 2025 Golden Globes.

The actress delivered a moving monologue as she accepted the award for Best Actress in a Motion Picture—Musical or Comedy for her performance in the body horror film The Substance, revealing she once thought her career in Hollywood had already peaked.  

“Thirty years ago, I had a producer tell me that I was a popcorn actress, and at that time, I made that mean that this wasn’t something that I was allowed to have,” Demi told the audience at the Beverly Hilton Jan. 5 as she held her award. “That I could do movies that were successful, that made a lot of money, but that couldn’t be acknowledged. And I bought in, and I believed that.”

She went shared that the moniker slowly “corroded” her outlook on her career, leading her to wonder if she had “done what I was supposed to do.”

“As I was at a low point,” she continued, “I had this magical, bold, courageous, out of the box, absolutely bonkers script come across my desk called The Substance, and the universe told me, ‘You’re not done.’”

Rich Polk/GG2025/Penske Media via Getty Images

The first-time Golden Globe winner—who shares daughters Rumer Willis, 36, Scout Willis, 33, and Tallulah Willis, 30, with ex Bruce Willis—used her experience to encourage others not to discount their own paths.

“In those moments when we don’t think we’re smart enough, or pretty enough, or skinny enough, or successful enough, or basically just not enough,” she went on, “I had a woman say to me, ‘Just know you will never be enough, but you can know the value of your worth if you just put down the measuring stick.’”

Demi said in conclusion, “I celebrate this as a marker of my wholeness and of the love that is driving me and for the gift of doing something I love and being reminded that I do belong.”

Keep reading to see who else won big at the 2025 Golden Globes.

Best Motion Picture—Drama

WINNER: The Brutalist

A Complete Unknown

Conclave

Dune: Part Two

Nickel Boys

September 5

Best Motion Picture—Musical or Comedy

Anora

Challengers

WINNER: Emilia Pérez

A Real Pain

The Substance

Wicked

Best Actress in a Motion Picture—Musical or Comedy

Amy Adams, Nightbitch

Cynthia Erivo, Wicked

Karla Sofía Gascón, Emilia Pérez

Mikey Madison, Anora

WINNER: Demi Moore, The Substance

Zendaya, Challengers

Best Actress in a Motion Picture—Drama

Pamela Anderson, The Last Showgirl

Angelina Jolie, Maria

Nicole Kidman, Babygirl

Tilda Swinton, The Room Next Door

WINNER: Fernanda Torres, I’m Still Here

Kate Winslet, Lee

Best Actor in a Motion Picture—Drama

WINNER: Adrien Brody, The Brutalist

Timothée Chalamet, A Complete Unknown

Daniel Craig, Queer

Colman Domingo, Sing Sing

Ralph Fiennes, Conclave

Sebastian Stan, The Apprentice

Best Supporting Actress—Series, Miniseries or Motion Picture Made for Television

Liza Colón-Zayas, The Bear

Hannah Einbinder, Hacks

Dakota Fanning, Ripley

WINNER: Jessica Gunning, Baby Reindeer

Allison Janney, The Diplomat

Kali Reis, True Detective: Night Country

Best Actress in a Television Series—Drama

Kathy Bates, Matlock

Emma D’Arcy, House of the Dragon

Maya Erskine, Mr. and Mrs. Smith

Keira Knightley, Black Doves

Keri Russell, The Diplomat

WINNER: Anna Sawai, Shogun

Best Supporting Actress—Motion Picture

Selena Gomez, Emilia Pérez

Ariana Grande, Wicked

Felicity Jones, The Brutalist

Margaret Qualley, The Substance

Isabella Rossellini, Conclave

WINNER: Zoe Saldaña, Emilia Pérez

Best Television Series—Musical or Comedy

Abbott Elementary

The Bear

The Gentlemen

WINNER: Hacks

Nobody Wants This

Only Murders in the Building

Best Miniseries or Motion Picture—Television

WINNER: Baby Reindeer

Disclaimer

Monsters: The Lyle and Erik Menendez Story

The Penguin

Ripley

True Detective

Best Television Series—Drama

The Day of the Jackal

The Diplomat

Mr. and Mrs. Smith

WINNER: Shogun

Slow Horses

Squid Game

Best Supporting Actor—Series, Miniseries or Motion Picture Made for Television

WINNER: Tadanobu Asano, Shogun

Javier Bardem, Monsters: The Lyle and Erik Menendez Story

Harrison Ford, Shrinking

Jack Lowden, Slow Horses

Diego Luna, La Máquina

Ebon Moss-Bachrach, The Bear

Best Actor in a Miniseries or Motion Picture—Television

WINNER: Colin Farrell, The Penguin

Richard Gadd, Baby Reindeer

Kevin Kline, Disclaimer

Cooper Koch, Monsters: The Lyle and Erik Menendez Story

Ewan McGregor, A Gentleman in Moscow

Andrew Scott, Ripley

Best Actor in a Television Series—Drama

Donald Glover, Mr. and Mrs. Smith

Jake Gyllenhaal, Presumed Innocent

Gary Oldman, Slow Horses

Eddie Redmayne, The Day of the Jackal

WINNER: Hiroyuki Sanada, Shogun

Billy Bob Thornton, Landman

Best Supporting Actor—Motion Picture

Yura Borisov, Anora

WINNER: Kieran Culkin, A Real Pain

Edward Norton, A Complete Unknown

Guy Pearce, The Brutalist

Jeremy Strong, The Apprentice

Denzel Washington, Gladiator II

Best Actor in a Motion Picture—Musical or Comedy

Jesse Eisenberg, A Real Pain

Hugh Grant, Heretic

Gabriel LaBelle, Saturday Night

Jesse Plemons, Kinds of Kindness

Glen Powell, Hit Man

WINNER: Sebastian Stan, A Different Man

Best Actress in a Television Series—Musical or Comedy

Kristen Bell, Nobody Wants This

Quinta Brunson, Abbott Elementary

Ayo Edebiri, The Bear

Selena Gomez, Only Murders in the Building

Kathryn Hahn, Agatha All Along

WINNER: Jean Smart, Hacks

Best Actress in a Miniseries or Motion Picture—Television

Cate Blanchett, Disclaimer

WINNER: Jodie Foster, True Detective: Night Country

Cristin Milioti, The Penguin

Sofía Vergara, Griselda

Naomi Watts, Feud Capote vs. the Swans

Kate Winslet, The Regime

Best Actor in a Television Series—Musical or Comedy

Adam Brody, Nobody Wants This

Ted Danson, A Man on the Inside

Steve Martin, Only Murders in The Building

Jason Segel, Shrinking

Martin Short, Only Murders in The Building

WINNER: Jeremy Allen White, The Bear

Best Motion Picture—Animated

WINNER: Flow 

Inside Out 2

Memoir of a Snail

Moana 2

Wallace & Gromit: Vengeance Most Fowl

The Wild Robot

Best Original Song—Motion Picture

“Beautiful That Way,” The Last Showgirl 

“Compress/Repress,” Challengers 

WINNER: “El Mal,“ Emilia Pérez  

 “Forbidden Road,” Better Man

“Kiss the Sky,” The Wild Robot

“Mi Camino,” Emilia Pérez

Best Cinematic and Box Office Achievement—Motion Picture

Alien: Romulus

Beetlejuice Beetlejuice

Deadpool & Wolverine

Gladiator 2

Inside Out 2

Twisters

WINNER: Wicked

The Wild Robot

Watch the 2025 Golden Globes on CBS tonight, Jan. 5, at 8 p.m. ET/5 p.m. PT. And don’t miss E!’s Live From E! red carpet show starting at 6 p.m. ET/3 p.m. PT.