Monday Night Football: Lions vs. 49ers

The final game of Week 17 will be a Monday Night Football contest between the Detroit Lions (13-2) on the road against the San Francisco 49ers (6-9).

The Niners lead the all-time series between these teams, 38-27-1, and have won 11 of their 12 most-recent regular season meetings. However, they haven’t faced off since 2021, and a lot has changed in Detroit since then. They’ve met three times in the postseason over the years, most recently back in January, when the 49ers barely beat the Lions, 34-31, in the NFC Championship game.

Despite going against your instincts, rooting for the 49ers is the way to go, as explained by Bleeding Green’s BLG:

“DETROIT LIONS at SAN FRANCISCO 49ERS: Eagles fans don’t typically enjoy rooting for the 49ers but San Francisco is already eliminated from playoff contention. Winning only serves to worsen their draft position and help the Eagles potentially get the No. 1 seed. Root for the 49ers.”

Here’s everything you need to know about tonight’s games.

Detroit Lions vs. San Francisco 49ers
TV Schedule
Game time: 8:15 PM EST
Channel: ESPN
Location: Levi’s Stadium | Santa Clara, CA

Online Streaming
ESPN+ | FuboTV

Odds via FanDuel

Detroit Lions: -3.5 (-188)

San Francisco 49ers: +3.5 (+158)

Over/under: 50.5 points

Open thread: Discuss Monday night’s game in the comments below.